The honeymoon phase in Sudanese children with type 1 diabetes mellitus

Intisar A Khider, Mariam Z Mubarak, Ilham M Omer, Mohamed A Abdalla

Abstract


Background  The honeymoon period (HP) refers to the period of time shortly after the diagnosis of type 1 diabetes mellitus (T1DM), during which there is some  restoration of insulin production by the pancreas, a temporary phase during which there is glycemic control and with longer period there is chance to delay potential complications. Recently researches focused on prolongation or permanence of the period. However very limited data is available in literature and this is the first study from Sudan.   
Objectives to a) investigate for the frequency of occurrence of the HP among Sudanese diabetic children, b) study its onset, duration and influential factors, c) recognize potential impacts and family attitude after the honeymoon period gets over   and d) assess doctors attitude during  HP.
Methods This is a cross-sectional hospital-based study on HP among children with T1DM in three specialized diabetic clinics in Khartoum State. Those who presented during the period June-Sept 2011were included and data was collected using personal interviews.  
Results A total of 136 patients with T1DM were enrolled; 26(19.1%) of them experienced the HP; 15(57.7%) were males and 11(42.3%) were females. The duration of time from the onset of DM till remission was 3.2 ± 6.3 (mean ± SD) months. Twenty two (84.6%) patients recognized the HP through low blood glucose level, 4(15.4%) had frequent attacks of hypoglycemia and decreased insulin requirements. The mean duration of the HP was 5.4 ± 12.9 months. Insulin requirements were 0.4 U/kg/day in 14(53.8%) patients during the HP while 0.5-0.7 U/kg/day was needed in 13(55.6%) patients after recovery. Age of onset was below 5 years in 7(26.9 %) patients while 19(73.1%) patients were 5 years and above. HBA1c measurements, 3 months after the HP were 5.8-6.1 % in 15(62.5%) patients,   5.4-5.7% in 4(16.8%) and 5-5.3% in 5(20.8%) patients. Conclusion Sudanese children with T1DM experience HP in a frequency lower than that recorded in other countries.

Keywords


The honeymoon phase;Sudanese children;diabetes mellitus

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References


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The honeymoon phase in Sudanese children with type 1 diabetes mellitus

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