Haemostatic studies in Sudanese women on oral contraceptive pills

TM Abdalla, AAY Kordofani, AAH Nimir


The thrombophilic effect of contraceptive pills has widely been studied. This is the first study in Sudan addressing this issue. The study aimed at detection of haemostatic derangements in Sudanese women using contraceptive pills containing oestrogen and progesterone (combined pills) or progesterone only (mini pills) for short and long duration.
Materials and Methods:
Healthy Controls: 50 apparently healthy Sudanese women not on the pill.
Study group: 50 Sudanese women on the pill for periods of 1-30 months; 25 on combined pills, and 25 on mini pills.
Laboratory methods: platelet count, PT,PTT and fibrinogen level were done for all studied women using semi-automated methods.
Results: mean values for platelets, PT, PTT and fibrinogen were normal for both controls and study group but compared to controls mean PT and PTT were significantly shorter in users of combined pills while platelet counts and fibrinogen levels were significantly higher. Use of mini pills did not cause any deviation from normal. Duration of use did not affect results.
Conclusion: Combined pills pose a real risk of developing thromboembolic disease by causing a hypercoagulable state. As reported in the literature the use of mini pills is safer though less efficient in contraception.

Full Text:



  • There are currently no refbacks.

ISSN: 1858-5345