Effect of blood pressure on heart rate variability

Mohamed Faisal Lutfi, Mohamed Yosif Sukkar

Abstract


Introduction: previous studies have reported decreased heart rate variability (HRV) among subjects with hypertension, which explains the high morbidity and mortality rates in these patients. The aim of this study was

to detect the relationship between blood pressures and HRV in people with no history of hypertension.

Materials and Methods: the study involved twenty-eight apparently healthy males (age mean (M) ± standard deviation (SD) = 24.86±3.79) and twenty-eight females (age M± SD = 25.14±5.37). Subjects with past medical

history suggestive of diabetes mellitus, hypertension, heart diseases or any illness that may alter heart rate were excluded. The blood pressure and HRV were measured for each subject. Screening studied variables

for significant correlation between blood pressures and heart rate variability indices were performed using bivariate and partial correlations. P < 0.05 was considered significant.

Results: high diastolic blood pressure (DBP) was associated with depressed SDNN, RMSSD (correlation coefficients (CC) = -0.37, P = 0.009 for both). Systolic blood pressure (SBP) correlated positively with both LF

Norm and LF/HF (CC = 0.33, P = 0.021 for LF Norm and CC = 0.33, P = 0.021 for LF/HF) and negatively with HF Norm (CC = -0.29, P = 0.045). DBP correlated positively with both LF Norm and LF/HF (CC = 0.34, P =

0.017 for LF Norm and CC = 0.33, P = 0.021 for LF/HF) and negatively with TP (CC = -0.32, P = 0.025), LF (CC = -0.31, P = 0.032), HF (CC = -0.35, P = 0.014) and HF Norm (CC = -0.34, P = 0.017). High mean arterial

blood pressure (MABP) was associated with low SDNN, RMSSD (CC = -0.35, P = 0.015 for SDNN and CC = -0.35, P = 0.013 for RMSSD), HF (CC = -0.33, P = 0.023) and HF Norm (CC = -0.40, P = 0.005). However,

MABP correlated positively with both LH Norm (CC = 0.40, P = 0.005) and LF/HF (CC = 0.37, P = 0.009).

Conclusion: Lower HRV (SDNN, RMSSD, TP, HF and LF in absolute units), reduced vagal tone (HF Norm) and higher sympathetic function (LF Norm and LF/HF) were associated with higher values of blood

pressures putting subjects with such trends at a higher risk of developing hypertension. Relevance of HRV to health counseling was discussed.

*Corresponding author: Assistant Professor of Physiology, Faculty of Medicine, AlNeelain University. Email:moh12312@yahoo.co.uk.


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ISSN: 1858-5345