Case Report Primary squamous cell carcinoma of the thyroid gland on underlying thyroiditis

Mohamed Eisam Elhag, Hassan Ahmad Mohammed, Alawia Mirgani Mansour Taha, Mohamed ElMakki Ahmed

Abstract


We report a case of primary squamous cell carcinoma of the thyroid with focal lymphocytic thyroiditis. A
45-year old Sudanese female presented with difficulty in breathing, hoarseness of voice and a painful hard
thyroid swelling of 6 months duration. She gave a history of hyperthyroidism 4 month prior to admission
and was treated with Carbimazole. On presentation there was a hard tender diffuse swelling affecting
mainly the left lob of the thyroid. A thoracic inlet X-ray showed marked tracheal deviation and a C.T.
scan showed possible local invasion of the trachea and carotid space. She underwent successful palliative
near-total thyroidectomy for a locally advanced tumour followed by tracheostomy. Histopathology
showed infiltrating moderately differentiated squamous cell carcinoma with simple colloid goitre with
regenerative degenerative change and focal areas of Lymphocytic thyroiditis. The patient received 2 cycles
of chemotherapy and succumbed 2 months later.

Keywords


Case ;Report ;Primary ;squamous cell ;carcinoma of the ;thyroid; gland on; underlying ;thyroiditis

Full Text:

PDF

References


Syed MI, Stewart M, Syed S et al. Squamous

cell carcinoma of the thyroid: primary or

secondary disease? J Laryngol Otol 2011,125:3

– 9.

Fargol B, Sebo TJ, Kasperbauer JL, Fatourechi

V. Primary squamous cell carcinoma of the

thyroid: Report of 10 cases. Thyroid 2006;16:89

– 94.

Fassan M, Pennelti G, Pelizzo MR, Rugge

M. Primary squamous cell carcinoma of the

thyroid: Immunohistochemical profile and

literature review. Tumori 2007;93:518 – 521.

Makay O, Kaya T, Ertan Y et al. Primary

squamous cell carcinoma of the thyroid: report

of three cases. Endocr J 2008;55:359-364

Long JL, Strocker AM, Wang MB, Blackwell

KE: EGFR expression in primary squamous

cell carcinoma of the thyroid. Laryngoscope

; 119: 89-90.

Luca Reggiani Bonetti, Massimo Lupi,

Margherita Trani et al. EGFR polysomy in

squamous cell carcinoma of the thyroid. Report

of two cases and review of the literature. Tumori

;96:503-507.

Primary squamous cell carcinoma of the thyroid gland on underlying thyroiditis

Tunio MA, Al Asiri M, Fagih M, Akasha R.

Primary squamous cell carcinoma of thyroid: a

case report and review of literature. Head Neck

Oncol. 2012;4:8.

Shrestha M, Sridhara SK, Leo LJ, Coppit GL

rd, Ehrhardt NM8. Primary squamous cell

carcinoma of the thyroid gland: A case report

and review. Head Neck. 2013;35: 299-303.

Müssig K, Dahm J, Koitschev A et al. Primary

squamous cell carcinoma of the thyroid. Intern

Med J 2008;38: 69-70.

Sanchez-Sosa S, Rios-Luna NP, Tamayo Bdel

R, Simpson K,Albores-Saavedra J: Primary

squamous cell carcinoma of the thyroid arising

in Hashimoto’s thyroiditis in an adolescent.

Pediatr Dev Pathol 2006; 9: 496-500.


Refbacks

  • There are currently no refbacks.


ISSN: 1858-5345