The effect of ethanolic leaves extract of Solenostemma argel on blood electrolytes and biochemical constituents of albino rats

Authors

  • Osman Hisham M. Department of Biochemistry, Faculty of Pharmacy, National Ribat University
  • M H Shayoub Department of Pharmaceutics, Faculty of Pharmacy, University of Khartoum
  • Babiker E M Department of Zoology, Faculty of Science, University of Khartoum
  • Mounzer M. Elhag Department of Biochemistry, Faculty of Medicine, University of Gadarf

DOI:

https://doi.org/10.53332/sjs.v6i1.384

Keywords:

Solenostemma argel, medicinal plant, electrolytes, glomerular filtration rate, AST, ALP, ALT, liver function, kidneys function

Abstract

The ethanolic leaves extract of S. argel was studied for its effect on the blood electrolytes and biochemical constituents of albino rats. The animals (n= 12, average BW= 240 g) were divided into two groups of six each: one to act as the experimental group (EG) and the other as the control group (CG). The result Revealed that K, Ca and P for electrolytes and creatinine, urea, aspartate aminotransferase (AST) and alkaline phosphatase (ALP) for biochemical constituents were found significantly higher (P < 0.05) in experimental group when compared with the control group. In the meantime, total protein, albumin, total bilirubin, and alanine aminotransferase (ALT) for biochemical constituents, and Na and Fe for electrolytes did not differ significantly from those of the control group (P > 0.05). The findings of this study suggested that the dose 600 mg of extract /Kg BW was more likely to have adverse effect on liver and kidneys of albino rats.

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Published

2021-10-06

Issue

Vol. 6 No. 1 (2014): Sudan Journal of Science

Section

Articles