Review Article: The role of Neo adjuvant Chemotherapy in the treatment of Breast Cancer

Authors

  • Kamal Eldein Hamed Mohamed University of Khartoum, 2 The Radiation and Isotopes Center of Khartoum
  • Muna Mohamed Ahmed Kaboush University of Khartoum, 2 The Radiation and Isotopes Center of Khartoum
  • Abdelsamie Abdalla Mohamed University of Khartoum, 2 The Radiation and Isotopes Center of Khartoum

Keywords:

Review Article The role of Neo adjuvant Chemotherapy in the treatment of Breast Cancer

Abstract

Neoadjuvant chemotherapy (NACT) in breast cancer is giving chemotherapy before surgery, it’s an effective
initial treatment for large tumors, locally advanced cancer and inflammatory breast cancer. It downstage
the disease, allow lesser extensive surgery e.g. breast conservative surgery, the benefit is greater for those
who attain pathological complete response (PCR), who get a significantly better overall survival (OS), and
progression free survival (PFS), compared with those who don’t. This approach is very important in Sudan
where the majority, almost 65 % of patients present with locally advanced disease, most of them are denied
this treatment.

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Published

2023-01-22

Issue

Vol. 8 No. 2 (2015): Khartoum Medical Journal

Section

Articles