An uncommon presentation of primary gastro-intestinal non- Hodgkin’s lymphoma (PGINHL) with multiple jejunal strictures in a young patient

Abstract

Introduction:
Primary gasrointesinal non-Hodgkin’s lymphoma (PGINHL) is a heterogeneous complex disease (1).
Variations in patients’ characterisics, clinical sages, hisologic sub-types, and treatment options depend
largely on the site of origin (1, 2). In fact, gasrointesinal tract is the mos commonly involved site for
primary NHL occurrence, accounting for nearly 20–40% of all extra-nodal disease (2). It arises from the
lymphoid tissues within the wall of small intesine which are more abundant in the ileum (3), being either
localized to a single segment of the small intesine, or multi-centric in 15–20% (3). Clinical presentation is
extremely variable with a wide range of presenting symptoms like: non-specifc abdominal pain; anorexia
and weight loss; diarrhea; subacute obsruction; and a palpable abdominal mass (2, 4-6), with an emergency
surgical treatment being required in 11–64 % of cases (4). Herein, authors describe an unusual presentation
of a PGI   NHL in a young Sudanese patient who suffered from recurrent episodes of subacute small bowel
obsruction due to multiple jejunal srictures (simulating Crohn’s disease clinically and radiologically) and
found to have a diffuse large B-cell lymphoma on hisopathological examination of the surgical specimen.